Fumihiro Saika Selected Research

clozapine N-oxide

12/2021	Chemogenetic Activation of CX3CR1-Expressing Spinal Microglia Using Gq-DREADD Elicits Mechanical Allodynia in Male Mice.
1/2021	Chemogenetic activation of central gastrin-releasing peptide-expressing neurons elicits itch-related scratching behavior in male and female mice.
1/2020	Chemogenetic Regulation of CX3CR1-Expressing Microglia Using Gi-DREADD Exerts Sex-Dependent Anti-Allodynic Effects in Mouse Models of Neuropathic Pain.

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Fumihiro Saika Research Topics

Disease

13	Neuralgia (Stump Neuralgia) 01/2019 - 01/2009
11	Hyperalgesia 12/2021 - 01/2009
5	Pain (Aches) 12/2021 - 01/2009
5	Neuroinflammatory Diseases 01/2019 - 01/2009
3	Neoplasms (Cancer) 01/2020 - 08/2014
2	Inflammation (Inflammations) 08/2014 - 04/2014
1	Hypersensitivity (Allergy) 12/2021
1	Pruritus (Itching) 01/2021
1	Contact Dermatitis (Eczema, Contact) 01/2020
1	Type 2 Diabetes Mellitus (MODY) 01/2019
1	Peripheral Nerve Injuries 03/2018
1	Intractable Pain 03/2018
1	Nervous System Diseases (Neurological Disorders) 01/2014
1	Lymphoma (Lymphomas) 01/2009
1	Leukemia 01/2009

Drug/Important Bio-Agent (IBA)

6	LigandsIBA 01/2020 - 12/2013
4	ChemokinesIBA 11/2017 - 10/2010
4	CytokinesIBA 11/2017 - 01/2009
4	CC ChemokinesIBA 08/2014 - 10/2010
3	clozapine N-oxideIBA 12/2021 - 01/2020
3	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2019 - 11/2017
2	TC 2559IBA 01/2019 - 03/2018
2	Opioid Analgesics (Opioids)IBA 06/2015 - 07/2009
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2015 - 01/2009
2	Neutralizing AntibodiesIBA 05/2015 - 10/2010
2	Vincristine (Oncovin)FDA LinkGeneric 07/2009 - 01/2009
1	pexidartinibIBA 12/2021
1	diphenylcyclopropenoneIBA 01/2020
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2020
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2020
1	LipopolysaccharidesIBA 01/2019
1	SaporinsIBA 01/2019
1	AminesIBA 01/2019
1	sazetidine-AIBA 03/2018
1	Interleukin-13IBA 01/2017
1	Analgesics (Analgesic Drugs)IBA 06/2015
1	Liposomes (Liposome)IBA 05/2015
1	Fingolimod Hydrochloride (FTY720)FDA Link 05/2015
1	Clodronic Acid (Clodronate)IBA 05/2015
1	GlucocorticoidsIBA 05/2015
1	Therapeutic UsesIBA 04/2015
1	Interleukin-4 (Interleukin 4)IBA 04/2015
1	Tyrosine (L-Tyrosine)FDA Link 04/2014
1	Phosphotransferases (Kinase)IBA 04/2014
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2014
1	CXCR ReceptorsIBA 04/2014
1	Methamphetamine (Desoxyn)FDA LinkGeneric 01/2014
1	Histones (Histone)IBA 12/2013
1	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 07/2009
1	CarrageenanIBA 07/2009
1	Imipramine (Janimine)FDA LinkGeneric 07/2009
1	Morphine (MS Contin)FDA LinkGeneric 07/2009
1	Antineoplastic Agents (Antineoplastics)IBA 01/2009
1	Interleukin-6 (Interleukin 6)IBA 01/2009

Therapy/Procedure

5	Ligation 01/2020 - 10/2010
3	Drug Therapy (Chemotherapy) 01/2019 - 11/2017
2	Therapeutics 01/2021 - 11/2017